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The influence of different doses of dexmedetomidine nasal drops on the postoperative recovery quality of children

The influence of different doses of dexmedetomidine nasal drops on the postoperative recovery quality of children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124452
Enrollment
Unknown
Registered
2026-05-12
Start date
2023-06-07
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium

Interventions

Group a:Based on the weight of the child patient, calculate the total dose of dexmedetomidine at 0.5ug/kg, dilute it to 1ml (diluted with normal saline), and slowly drip it into the nasal cavity, 0.5m
Group b:Based on the weight of the child patient, calculate the total dose of dexmedetomidine at 1.0ug/kg, dilute it to 1ml (diluted with normal saline), and slowly drip it into the nasal cavity, 0.5m
Group c:1ml of 0.9% sodium chloride injection for nasal drops, 0.5ml in each of the left and right nostrils

Sponsors

Xiamen University First Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 7 Years

Inclusion criteria

Inclusion criteria: Children aged 3 to 7 years with ASAI-II grade who are scheduled for elective surgery

Exclusion criteria

Exclusion criteria: 1. Nasal approach surgery; 2. Known severe heart and lung diseases; 3. Neuromuscular diseases; 4. BMI = 30 kg/m2; 5. Patients with severe upper respiratory tract infections who are advised to postpone the surgery; 6. Those who have not obtained the right to informed consent; 7. Patients with drug allergies; 8. Patients with abnormal intellectual development.

Design outcomes

Primary

MeasureTime frame
Pediatric Anesthesia Emergence Delirium (PAED) Score;Visual Analogue Scale (VAS) score for pain;

Secondary

MeasureTime frame
Pulse oxygen saturation (SpO2);Mean arterial pressure (MAP);Heart Rate (HR);Dosage of general anesthetic drugs;

Countries

China

Contacts

Public ContactHan Mingjie

Xiamen University First Affiliated Hospital

hanmingjieh@sina.com+86 139 5923 7296

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026