Subclavian Artery Stenosis/occlusion
Conditions
Interventions
subclavian artery stenosis group:None
subclavian artery occlusion group:None
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 years or older with atherosclerotic cardiovascular disease (ASCVD); 2.Digital subtraction angiography (DSA) demonstrating diameter stenosis =70% or total occlusion, with planned stent implantation; 3.Symptomatic upper limb ischemia, posterior circulation ischemia, or myocardial ischemia following coronary artery bypass grafting (CABG) [+ definition]; 4.Subclavian steal: Complete or partial subclavian steal syndrome (confirmed by in-hospital ultrasonography or angiography), or an inter-arm systolic blood pressure difference > 30 mmHg; 5.Tolerance to pharmacological treatment including aspirin, clopidogrel, and heparin; 6.Participants and their families understand and sign the informed consent form, agree to pre- and post-operative blood sample collection, and authorize the use of samples for scientific research.
Exclusion criteria
Exclusion criteria: 1.Conditions causing severe arrhythmia or significant blood pressure fluctuations during measurement, such as atrial fibrillation; 2.Limb loss, deformity, or pain at the site of blood pressure measurement; 3.Non-atherosclerotic diseases, such as Takayasu arteritis; 4.Presence of an arteriovenous fistula (AVF) in the upper limbs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subclavian artery residual stenosis;Postoperative inter-arm systolic blood pressure difference;Surgery success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| 2-year cumulative patency rate;Any stroke or death within 30 days;Any stroke, death, or cardiovascular event within 2 years; | — |
Countries
China
Contacts
Public ContactLiqun Jiao
Xuanwu Hospital, Capital Medical University
Outcome results
None listed