subclinical hypoxemia (SpO2 90–94%) and hypoxemia (SpO2 < 90%)
Conditions
Interventions
Group H2: High-flow HFNC group (FiO2 40%, flow rate 50 L/min):None
Group H1: Low-flow HFNC group (FiO2 40%, flow rate 30 L/min):None
Group C: Conventional low-flow oxygen therapy via nasal cannula:None
Sponsors
Chongqing General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years. 2. American Society of Anesthesiologists (ASA) physical status II–III. 3. 18 kg/m² < Body mass index (BMI) < 35 kg/m². 4. Patients undergoing ERCP under sedation or anesthesia. 5. Procedure duration between 40 and 120 minutes; 6. Complete clinical data available.
Exclusion criteria
Exclusion criteria: 1. Significant upper airway abnormalities or intracranial conditions, including severe nasal obstruction, recent nasal trauma or bleeding, markedly elevated intracranial pressure, or skull base fracture 2. Severe respiratory diseases such as pneumothorax, COPD, severe upper airway stenosis, a known difficult airway, or severe obstructive sleep apnea 3. Severe cardiovascular or cerebrovascular diseases 4. Coagulation disorders, severe hepatic dysfunction, or upper gastrointestinal bleeding with shock 5. Baseline oxygen saturation < 93% 6. Significant missing clinical data 7. Conversion to endotracheal intubation during ERCP;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| arterial blood gas parameters (PaO2, PaCO2);arterial blood gas parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of subclinical hypoxemia (SpO2 90–94%) and hypoxemia (SpO2 < 90%);patient and operator satisfaction;incidence of airway interventions; | — |
Countries
China
Contacts
Public ContactXin Qiao
Chongqing General Hospital
Outcome results
None listed