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Precise Volume Management for Preserving Residual Renal Function in Incident Hemodialysis Patients: A Pilot Clinical Trial

Precise Volume Management for Preserving Residual Renal Function in Incident Hemodialysis Patients: A Pilot Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124360
Enrollment
Unknown
Registered
2026-05-11
Start date
2021-03-06
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage renal disease

Interventions

Experimental group:The intervention group received a precise volume management strategy. A specialized management team assessed the patients' dry weight using a bioelectrical impedance analysis device
Control Group:Dry weight was assessed and ultrafiltration volume was determined using clinical evaluation methods, without the administration of diuretics.

Sponsors

Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 18–80 years; 2. Newly started on hemodialysis, expected to undergo hemodialysis at our hospital for >12 months; 3. Urine output >200ml/day; 4. No metal joint prostheses, cardiac stents, pacemakers, or other metal objects in the body that may interfere with bioelectrical impedance measurement; 5. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Complicated severe infections, heart failure; 2. Malignant tumors, active pulmonary tuberculosis, active lupus, severe liver disease, trauma, mental disorders; 3. Acute renal failure or patients switching from peritoneal dialysis to hemodialysis; 4. Long-term use of nephrotoxic drugs, amputation, pregnancy; 5. Patients taking other diuretics; 6. Patients with hypokalemia.

Design outcomes

Primary

MeasureTime frame
Urea clearance rate;

Secondary

MeasureTime frame
Incidence of Cardiovascular Disease;

Countries

China

Contacts

Public ContactHuang Chunxiang

Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University

908894540@qq.com+86 85827636

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026