Severe stenosis of the extracranial segment of the internal carotid artery combined with stenosis of the ipsilateral middle cerebral artery or severe stenosis of the initial segment of the unilateral vertebral artery combined with stenosis of the intracranial V4 segment
Conditions
Interventions
Gold Standard:Digital subtraction angiography, DSA
Index test:Transcranial Color Doppler and Transcranial Doppler Ultrasound
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with severe stenosis of the extracranial segment of the internal carotid artery or severe stenosis of the initial segment of the unilateral vertebral artery using integrated neck brain ultrasound; 2.Perform stent placement surgery within 2 weeks of ultrasound examination, and perform DSA and CTA examinations; 3.Age >= 18 years old; 4.Clinical data is complete.
Exclusion criteria
Exclusion criteria: 1.Bilateral temporal windows are not transparent to sound; 2.Patients with severe stenosis of the extracranial segment of the internal carotid artery have ipsilateral MCA occlusion/ipsilateral common carotid artery severe stenosis or occlusion; 3.Patients with severe stenosis of the extracranial segment of the internal carotid artery have severe stenosis of the contralateral carotid artery; 4.Patients with severe stenosis or occlusion of the anterior circulation in the initial segment of unilateral vertebral artery; 5.Severe stenosis or occlusion of bilateral subclavian arteries; 6.Vasospasm caused by subarachnoid hemorrhage, etc; 7.Related MCA or vertebral artery thrombolysis or endovascular treatment; 8.Arrhythmias such as atrial fibrillation or heart failure that affect velocity measurement; 9.CT, MRI, DSA examination contraindications or refusal of examination; 10.Severe bleeding disorders or coagulation dysfunction; 11.Merge serious diseases of other organs or tissues.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of intracranial artery stenosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| New stroke events;Clinical baseline indicators; | — |
Countries
China
Contacts
Public ContactYingqi Xing
Xuanwu Hospital Capital Medical University
Outcome results
None listed