FindTrial
Sign In

Dynamic Inflammatory Subphenotypes and Individualized PEEP in Patients with Severe Acute Respiratory Distress Syndrome

A Retrospective Study on Individualized PEEP Strategies for ARDS Patients Based on Dynamic Inflammatory Subphenotypes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124340
Enrollment
Unknown
Registered
2026-05-11
Start date
2026-05-18
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome

Interventions

Hyper-inflammatory group:none
Hypo-inflammatory group:none

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Duration of invasive mechanical ventilation = 24 hours; 2. ARDS patients (hospital-acquired ARDS diagnosis or meeting Berlin criteria); 3. Availability of 18 baseline variables for AI phenotype classifier calculations.

Exclusion criteria

Exclusion criteria: 1. Age < 18 years; 2. Acute heart failure.

Design outcomes

Primary

MeasureTime frame
28-day all-cause mortality;—

Secondary

MeasureTime frame
Days without the need for a ventilator (Day 28);Length of stay in the ICU;Total length of stay;—

Countries

China

Contacts

Public ContactLiang guopeng

West China Hospital of Sichuan University

liangguopeng007@163.com+86 189 8060 6154

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026