Thoracoscopic cardiac surgery
Conditions
Interventions
General anesthesia combined with intercostal nerve block group:Fifteen minutes after the patient had undergone general anesthesia, the same anesthesiologist with extensive experience in ultrasound-gui
Group with general anesthesia combined with local infiltration.:After the patient’s surgery and before skin suturing, the operating surgeon administers local infiltration of bupivacaine liposomes (133
Sponsors
Xiamen University Affiliated Cardiovascular Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 18-65 years old; 2. Selective thoracoscopic cardiac surgery; 3. Preoperative NRS score <= 1, no history of chronic pain; 4. Informed consent from patients and their families. ?
Exclusion criteria
Exclusion criteria: 1. Allergic to bupivacaine liposomes or local anesthetics; 2. Coagulation dysfunction; 3. Infection, deformity or pleural adhesions at the puncture site; 4. Severe liver and kidney dysfunction; 5. Cognitive impairment or inability to cooperate with assessment; 6. Pregnant/lactating women; 7. Individuals who have used long-acting local anesthetics or opioid drugs in the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS scores for postoperative rest and coughing.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Daily opioid medication dosage post-surgery (converted to morphine equivalent dose).;Time required for the first instance of self-administered pain relief.;QoR-15 score 24 hours post-surgery.;Incidence of perioperative adverse events (e.g., nausea, vomiting, constipation, drowsiness).;Length of stay in the ICU.;Total hospital stay time.;Levels of inflammatory factors TNF-a, IL-6, and IL-1ß in the serum before surgery, 24 hours after surgery, and 72 hours after surgery.; | — |
Countries
China
Contacts
Public ContactYan Pianpian
Xiamen University Affiliated Cardiovascular Hospital
Outcome results
None listed