Severe brain injury
Conditions
Interventions
Patients with severe craniocerebral injury:None
Sponsors
Xiamen Branch, Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria 1. The patient was diagnosed with severe craniocerebral injury through imaging examinations such as CT and magnetic resonance imaging (MRI), as well as clinical diagnosis. 2. Patients with a Glasgow Coma Scale (GCS) score of =16 years old; 4. Patients who have signed the informed consent form for the donation of bioinformatics samples in our hospital.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1.Age< 16 years old; 2.History of progressive neurological disorders; 3.Patients admitted to ICU multiple times; 4.Those whose family members give up treatment; 5.Important physiological parameters for calculating each scoring system are missing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical outcome ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic data: age, gender, underlying diseases, comorbidities (such as lung infection, renal failure, liver insufficiency, gastrointestinal dysfunction, water and electrolyte imbalance, hypoproteinemia, malnutrition, etc.);Laboratory results: Blood gas analysis, blood cell analysis, biochemical tests, coagulation function, D-dimer, PCT, CRP and other indicators;Intervention conditions within 24 hours after entering the ICU: dosage of vasoactive drugs, dosage of sedatives and analgesics, artificial hibernation, renal replacement therapy, mechanical ventilation, surgical intervention, etc;Imaging examination results: Head CT, MRI, etc;Critical care scores: GCS scores, SOFA scores, APACHEII scores, and OASIS scores, etc; | — |
Countries
China
Contacts
Public ContactLin Xiaoming
Xiamen Branch, Zhongshan Hospital, Fudan University
Outcome results
None listed