Post-Stroke Mild Cognitive Impairment
Conditions
Interventions
Combined group:taVNS 20 min/session + eye movement VR training 30 min/session
VR group:Sham stimulation (left auricle, no current delivery), eye movement VR training 30 min/session
The tavns group:Active stimulation (left auricle), traditional cognitive training for 30 minutes per session.
Control group:Sham stimulation (left auricle, no current), conventional cognitive training 30 min/session
Sponsors
Guangdong Sanjiu Brain Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Clinically confirmed ischemic stroke (according to the criteria of "Chinese Guidelines for the Prevention and Treatment of Cerebrovascular Diseases", confirmed by MRI/CT) 2. Stable neurological function (NIHSS= 3 months 4. Age 30-70 years old, audio-visual function can be combined with VR
Exclusion criteria
Exclusion criteria: 1.Severe aphasia (Western Aphasia Battery, WAB-AQ 17). 2.Implanted electronic devices (e.g., pacemaker), ear infection or metallic implants (contraindications for taVNS). 3.History of epilepsy, severe motion sickness or vestibular dysfunction (contraindications for VR). 4.Other neurological diseases (e.g., Parkinson’s disease, Alzheimer’s disease, psychiatric disorders).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood indicators;Neuroimaging indicators;Autonomic nerve function indicators;Autonomic nerve function indicators;Safety indicators; | — |
Countries
China
Contacts
Public ContactZhanhao Liu
Guangdong Sanjiu Brain Hospital
Outcome results
None listed