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Dynamic trajectory of epigenetic age and its correlation with short-term prognosis in the perioperative period of minimally invasive off-pump coronary artery bypass surgery

Dynamic trajectory of epigenetic age and its correlation with short-term prognosis in the perioperative period of minimally invasive off-pump coronary artery bypass surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124312
Enrollment
Unknown
Registered
2026-05-10
Start date
2026-05-11
Completion date
Unknown
Last updated
2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Observation group of minimally invasive bypass surgery without stopping the heart:None

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >=18 years; 2.Patients with good cognitive status who can actively cooperate and voluntarily sign the informed consent form

Exclusion criteria

Exclusion criteria: 1.Emergency surgery; 2.Preoperative need for intra-aortic balloon pump or mechanical ventilation support; 3.Left ventricular ejection fraction (LVEF) below 50%; 4.Severe liver or kidney failure; 5.Treatment with immunosuppressants or glucocorticoids within the last 3 months; 6.Hematological system diseases; 7.Cognitive dysfunction or inability to communicate; 8.History of alcohol or drug dependence or abuse; 9.Difficulty in follow-up or poor compliance

Design outcomes

Primary

MeasureTime frame
Methylation clock age;—

Secondary

MeasureTime frame
Postoperative delirium;Acute kidney injury;—

Countries

China

Contacts

Public ContactZhengqian Li

Peking University Third Hospital

zhengqianli@hsc.pku.edu.cn+86 10 8226 7260

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 16, 2026