Breast cancer
Conditions
Interventions
Group A (standard-dose combined exercise):Aerobic training: 5 days a week, 30 minutes each time (including warm-up/cool-down), target intensity RPE 11–13
Resistance training: 2 times a week, approximately 30 minutes each time, 8 fixed exercises (sitting-to-standing, step pedaling, seated rowing, standing bench press, external rotation of shoulders, ant
Full supervision during hospital radiotherapy period, online (check-in) + weekly follow-up supervision after discharge
Total intervention period 12 weeks.
Group B (Fragmented Equal-Dose Comprehensive Exercise):Aerobic training: 5 days a week, 3 times a day for 10 minutes each (with an interval of = 2 hours), total weekly minutes are equal to those of Gr
Target intensity: RPE 11–13
Resistance training: 6 times a week, each session lasts approximately 10 minutes, consisting of a micro-training unit of 3 movements (2 sets of each × 10–12 repetitions), cycling through units A/B/C,
The rest of the supervision and follow-up are the same as Group A
The total intervention period is 12 weeks.
Group B (Control):Receive the conventional radiotherapy care pathway and health education, without providing structured prescription-based exercise training and supervision
for ethical considerations, general exercise safety education can be provided.
Sponsors
Nanping First Hospital Affiliated to Fujian Medical University (Nanping First Hospital)
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Female, aged 18 to 75 years. 2. Pathologically confirmed breast cancer, having undergone surgery (breast-conserving surgery or modified radical mastectomy, etc.), and planning to receive adjuvant radiotherapy. 3. Baseline assessment can be completed and written informed consent can be signed before the start of radiotherapy. 4. ECOG 0-2, stable vital signs. 5. No contraindications to moderate-intensity exercise as assessed by the attending physician. 6. Able to understand and follow training instructions.
Exclusion criteria
Exclusion criteria: 1. Distant metastasis or need for urgent other anti-tumor treatmen. 2. Unstable cardiovascular/respiratory system diseases or other contraindications to exercise. 3. Resting blood pressure >= 180/110 mmHg or severe arrhythmia. 4. Severe hematological abnormalities or acute infection/fever (>= 38.0 deg C). 5. Current severe stage of breast cancer-related lymphedema (BCRL) or acute upper limb inflammation. 6. Severe cognitive/mental disorders that prevent cooperation. 7. The investigator deems the participant unsuitable for participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cancer-related fatigue; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality ;Upper limb function;Radiation dermatitis;Quality of Life ;physical activity;Compliance and Time Burden;Adverse event; | — |
Countries
China
Contacts
Public ContactQiandi Huang
Nanping First Hospital Affiliated to Fujian Medical University (Nanping First Hospital)
Outcome results
None listed