Elevated blood lipid margin
Conditions
Interventions
Control group:Replace household cooking oil with placebo (rapeseed oil), take 30 grams daily for 8 consecutive weeks.
Experimental group:Replace household cooking oil with the test substance (diglyceride oil), take 30 grams daily for 8 consecutive weeks.
Sponsors
Suzhou Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 18-65 years old, both genders are eligible; 2. BMI >= 30 kg/m^2, or total fat percentage: for men > 25%, for women > 30%; 3. Abnormal blood lipids: 5.18 mmol/L <= serum total cholesterol <= 6.21 mmol/L, or 1.70 mmol/L <= serum triglycerides <= 2.25 mmol/L; 4. Sign the informed consent form
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women, as well as those with pregnancy plans during the trial period; 2. Individuals with allergic constitution or who are allergic to glycerol diesters; 3. Those with severe diseases such as heart, liver, kidney and hematopoietic system disorders, and patients with mental illnesses; 4. Patients with hyperlipidemia. 5. Those who have taken lipid-lowering drugs in the past two weeks and whose judgment of the results is affected: Lipid-lowering drugs include: • Statins (such as Atorvastatin, Rosuvastatin) • Cholesterol absorption inhibitors (such as Ezetimibe) • Bile acid sequestrants (such as Fenofibrate, Bezafibrate) • Other drugs determined by the researchers to potentially affect the research results 6. Researchers consider the subjects to have poor compliance, or researchers consider that the subjects have any other conditions that are not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body fat content;Blood lipid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight;Adverse events and serious adverse events;Exercise Status Questionnaire Survey;72-hour dietary questionnaire survey;Renal function;Liver function;Blood routine test;Blood lipid;Subcutaneous fat thickness;Hip circumference;Waist circumference;Body Mass Index; | — |
Countries
China
Contacts
Public ContactZhang Jianwei
Suzhou Municipal Hospital
Outcome results
None listed