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A retrospective study of neuromuscular function and long-term functional outcome after anterior cruciate ligament reconstruction

A retrospective study of neuromuscular function and long-term functional outcome after anterior cruciate ligament reconstruction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124246
Enrollment
Unknown
Registered
2026-05-09
Start date
2026-05-20
Completion date
Unknown
Last updated
2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee anterior cruciate ligamnet injuries

Interventions

ACLR group and Healthy control group:None

Sponsors

The First Affiliated Hospital of the Army Medical University of the People's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. ACLR Group (1) Diagnosed with unilateral primary complete ACL rupture through MRI and clinical examination; (2) Underwent primary anatomical single-bundle or double-bundle ACLR, with autologous hamstring tendon or bone-patellar tendon-bone as the graft; (3) Age ranging from 18 to 45 years old, BMI: 18.5 - 24.9; (4) Had complete neuromuscular biomechanical assessment data before surgery, 3 months, 6 months, and 12 months after surgery. 2. Healthy Control Group (1) Age ranging from 18 to 45 years old, BMI: 18.5 - 24.9; (2) No history of knee trauma; (3) Normal knee range of motion, no lower limb biomechanical abnormalities, and normal neuromuscular function; (4) Complete data collection.

Exclusion criteria

Exclusion criteria: 1. ACLR group (1) Bilateral ACL injury or a significant injury history in the contralateral knee joint; (2) Combined with posterior lateral complex injury or multiple ligament injury (grade III) requiring surgical intervention; (3) Presence of neurological diseases or severe osteoarthritis (Kellgren-Lawrence = grade III) that affect functional assessment. 2. Healthy control group Those with severe diseases such as cardiovascular and cerebrovascular, liver and kidney, hematopoietic, neurological, and lumbar spine.

Design outcomes

Primary

MeasureTime frame
Knee injury and Osteoarthritis Outcome Score, KOOS;

Secondary

MeasureTime frame
Range of Motion, ROM;Victoria Institute of Sports Assessment Score, VISA;Anterior cruciate ligament - Quality of life;Tegner Activity Level Scale;Lysholm Knee Score;Tampa Scale for Kinesiophobia, TSK;Balance and Proprioception;Gait parameters;Muscle Strength Testing;International Knee Documentation Committee;Surface electromyography parameters;Single Leg Hop Test;Dynamic digital radiography parameters;7-Tesla Magnetic Resonance Imaging of the Knee Joint parameters;Basic parameters of fNIRs;fNIRs derived parameters;Motor evoked potential;Resting motor threshold;Activation of the motor threshold;Slope of the stimulus response curve;

Countries

China

Contacts

Public ContactGuo Lin

The First Affiliated Hospital of the Army Medical University of the People's Liberation Army of China

guolin6212@163.com+86 199 3817 7463

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 16, 2026