Knee anterior cruciate ligamnet injuries
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. ACLR Group (1) Diagnosed with unilateral primary complete ACL rupture through MRI and clinical examination; (2) Underwent primary anatomical single-bundle or double-bundle ACLR, with autologous hamstring tendon or bone-patellar tendon-bone as the graft; (3) Age ranging from 18 to 45 years old, BMI: 18.5 - 24.9; (4) Had complete neuromuscular biomechanical assessment data before surgery, 3 months, 6 months, and 12 months after surgery. 2. Healthy Control Group (1) Age ranging from 18 to 45 years old, BMI: 18.5 - 24.9; (2) No history of knee trauma; (3) Normal knee range of motion, no lower limb biomechanical abnormalities, and normal neuromuscular function; (4) Complete data collection.
Exclusion criteria
Exclusion criteria: 1. ACLR group (1) Bilateral ACL injury or a significant injury history in the contralateral knee joint; (2) Combined with posterior lateral complex injury or multiple ligament injury (grade III) requiring surgical intervention; (3) Presence of neurological diseases or severe osteoarthritis (Kellgren-Lawrence = grade III) that affect functional assessment. 2. Healthy control group Those with severe diseases such as cardiovascular and cerebrovascular, liver and kidney, hematopoietic, neurological, and lumbar spine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee injury and Osteoarthritis Outcome Score, KOOS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Range of Motion, ROM;Victoria Institute of Sports Assessment Score, VISA;Anterior cruciate ligament - Quality of life;Tegner Activity Level Scale;Lysholm Knee Score;Tampa Scale for Kinesiophobia, TSK;Balance and Proprioception;Gait parameters;Muscle Strength Testing;International Knee Documentation Committee;Surface electromyography parameters;Single Leg Hop Test;Dynamic digital radiography parameters;7-Tesla Magnetic Resonance Imaging of the Knee Joint parameters;Basic parameters of fNIRs;fNIRs derived parameters;Motor evoked potential;Resting motor threshold;Activation of the motor threshold;Slope of the stimulus response curve; | — |
Countries
China
Contacts
The First Affiliated Hospital of the Army Medical University of the People's Liberation Army of China