refractory overactive bladder in pediatrics
Conditions
Interventions
test group(PTNS group):Percutaneous Tibial Nerve Stimulation
control group(Solifenacin group):Solifenacin
test group(PTNS combined with Solifenacin group):Percutaneous Tibial Nerve Stimulation combined with Solifenacin Succinate Tablets
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
5 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for overactive bladder in children: (1) Urgency often accompanied by frequency, nocturia, enuresis, etc., with or without urge urinary incontinence; (2) Exclusion of urinary tract infection or definite pathological factors; 2. Meet the diagnostic criteria for refractory OAB: symptoms such as urgency and urinary incontinence persist after 12 weeks of medication treatment. 3. Age 5 to 18 years old (including 5 and 18 years old), any gender; 4. The child and their guardians voluntarily participate in this trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Exclude urinary frequency, urgency, and incontinence due to urinary tract infection, spinal cord injury, epilepsy, cerebral insufficiency, diabetes mellitus, and other neurological, urological, and endocrinological disorders. 2.Exclude the ontraindications to the use of solenacin, such as urinary retention , closed-angle glaucoma with uncontrolled symptoms, myasthenia gravis, severe ulcerative colitis, and toxic megacolon. 3.Allergy to the drug or some of the ingredients used in the test was excluded. 4.Patients who have participated or are participating in another clinical trial within 1 month. 5.Patients judged by the investigator to be unsuitable for participation in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total effective ratio; | — |
Countries
China
Contacts
Public ContactYang Jianhuan
The Second Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed