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A study on the application of liposomal bupivacaine for quadratus lumborum block in postoperative analgesia for elderly patients undergoing hip replacement surgery

A study on the application of liposomal bupivacaine for quadratus lumborum block in postoperative analgesia for elderly patients undergoing hip replacement surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124205
Enrollment
Unknown
Registered
2026-05-08
Start date
2025-11-07
Completion date
Unknown
Last updated
2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip joint diseases

Interventions

Liposomal Bupivacaine Group (Group B):Group B was injected with 133 mg (10 ml) of liposomal bupivacaine plus 15 ml of normal saline.
Ropivacaine group (Group R):Group R was injected with 25 ml of 0.25% ropivacaine.

Sponsors

The 960th Hospital of the Chinese People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for unilateral total hip arthroplasty (THA); 2. Age >= 65 years old, gender not limited; 3. American Society of Anesthesiologists (ASA) classification: I-III; 4. Signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. The patient or the patient's family refuses to participate in the study; 2. Those with a history of allergy to local anesthetics; 3. Those with skin infections at the puncture site; 4. Severe coagulation dysfunction; 5. Those with a history of chronic pain and long-term use of opioid drugs; 6. Those with severe liver or kidney dysfunction; 7. Those who cannot communicate normally with the doctor.

Design outcomes

Primary

MeasureTime frame
Record the quality of recovery score assessed by the QoR-15 scale;

Secondary

MeasureTime frame
Record the VAS scores of the two groups of patients;Record the postoperative muscle strength of the two groups of patients;Record the time of first ambulation after surgery, the consumption of opioids after surgery, and the rate of rescue analgesia in the two groups of patients.;Record the cumulative number of presses for patient-controlled intravenous analgesia after surgery in two groups of patients.;Record the postoperative hospital stay of the two groups of patients;Record the operation time and patients' analgesic satisfaction of the two groups of patients;Record the presence or absence of nerve block complications such as puncture hematoma, nerve injury, and infection, as well as adverse reactions such as dizziness, nausea, and vomiting in the two groups of patients.;

Countries

China

Contacts

Public ContactWang Fei

The 960th Hospital of the Chinese People's Liberation Army

zhoufuhe@163.com+86 531 5166 5482

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 16, 2026