Cavity Tumors
Conditions
Interventions
Experimental group:Perfusion LDH/EDTA
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.CT and MRI Scoring, Auxiliary Examination Diagnosis, and Pathological Diagnosis Confirm Cavity Tumors, Including: Non-Muscle-Invasive Bladder Cancer and Colorectal Cancer; 2.Age >= 18 years; 3.The cavity tumor is clearly diagnosed, and conventional treatments are ineffective or intolerable; 4.No severe dysfunction of vital organs such as the heart, liver, or kidneys; 5.Patients with bladder cancer must have non-muscle-invasive bladder cancer and either refuse or are unable to tolerate BCG instillation or radical cystectomy; 6.Patients must demonstrate good compliance and sign an informed consent form;
Exclusion criteria
Exclusion criteria: 1.Patients with severe comorbidities such as malnutrition, cachexia, ascites, or other terminal-stage tumor conditions. 2.Patients with underlying hematologic disorders such as coagulation factor abnormalities. 3.Patients with existing perforation or a significant risk of potential perforation. 4.Pregnant or lactating women. 5.Patients with concurrent multi-organ tumors, severe uncontrolled medical conditions, or acute infections. 6.Any medical history that, in the judgment of the investigator, may interfere with the trial results or increase patient risk. 7.Patients who are unable to comprehend the study objectives or do not agree to the study requirements. 8.Individuals lacking legal capacity or with restricted legal capacity. 9.The investigator determines that the patient has poor compliance and is unable to cooperate with sample collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor volume and recurrence-free rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary methylation assay value;Carcinoembryonic antigen (CEA) level;Complete organ preservation rate; | — |
Countries
China
Contacts
Public ContactYang Yan
Shanghai Tenth People's Hospital
Outcome results
None listed