None
Conditions
Interventions
Control group (Group C):Intravenous infusion of 0.9% sodium chloride solution
Lidocaine group (Group L):Intravenous infusion of lidocaine
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 30 to 80 years old; 2. ASAII-III; 3. BMI18-30kg/m^2; 4. Scheduled for lumbar fusion surgery; 5. Voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Cognitive impairment, psychiatric or neurological disorders; 2. Severe cardiac (NYHA class IV), hepatic (Child-Pugh class C), or renal (dialysis-dependent) insufficiency; 3. Bradycardia (heart rate < 50 beats per minute), second- or third-degree atrioventricular block; 4. Allergy or contraindication to the anesthetic drugs to be used; 5. Inability to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Fatigue Syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| pain;Incidence of intraoperative hypotension and bradycardia;Quality of postoperative recovery;Incidence of dizziness and pruritus;Plasma levels of inflammatory factors;Incidence of postoperative nausea and vomiting; | — |
Countries
China
Contacts
Public ContactGao Fang
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed