gallstones, abdominal pain, diarrhea, epigastric fullness, constipation, belching, bloating, vomiting, nausea, loss of appetite, regurgitation, heartburn
Conditions
Interventions
Observation group:None
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years, regardless of sex; 2.Has clear surgical indications and is clinically assessed by a physician as suitable for laparoscopic cholecystectomy (LC); 3. Diagnosed with benign gallbladder disease and scheduled to undergo LC at West China Hospital or the Day Surgery Center of West China Hospital, Sichuan University; 4. Capable of understanding the study procedures and voluntarily provides written informed consent; 5. Able to complete baseline assessments prior to surgery and follow-up visits at 1, 3, and 6 months postoperatively.
Exclusion criteria
Exclusion criteria: 1. Preoperatively confirmed or highly suspected concomitant common bile duct stones, gallbladder malignancy, or other biliary tract malignancies; 2. Complex biliary diseases identified on preoperative imaging or intraoperatively, such as Mirizzi syndrome or cholecystoenteric fistula (e.g., cholecystoduodenal fistula); 3.Presence of pre-existing conditions that may significantly confound the assessment of postoperative gastrointestinal symptoms, including inflammatory bowel disease, chronic pancreatitis, active peptic ulcer disease, gastrointestinal bleeding within the past 3 months, decompensated liver cirrhosis, or severe gastrointestinal motility disorders; 4. History of major prior gastrointestinal or biliary surgery that may substantially affect digestive function or bile metabolism; 5.Systemic corticosteroid or other immunosuppressive therapy continuously administered within the past 3 months, which the investigator considers likely to significantly influence outcome assessment; 6.Pregnant or lactating women; 7. History of alcohol or substance abuse within the past year that may impair study compliance or outcome interpretation; 8. Severe psychiatric disorder, cognitive impairment, language barrier, or any other condition that prevents the participant from providing informed consent, completing questionnaires, or attending follow-up visits; 9. Any other condition deemed by the investigator as unsuitable for study enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions within 180 days after laparoscopic cholecystectomy in patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions and complications within 180 days after laparoscopic cholecystectomy in asymptomatic patients;The incidence of complications associated with laparoscopic cholecystectomy; | — |
Countries
China
Contacts
Public ContactZhen You
West China Hospital of Sichuan University
Outcome results
None listed