Pelvic Floor Dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.pregnant women aged 18–45 years; 2.singleton pregnancy; 3.gestational age of 8–12 weeks; 4.absence of severe pregnancy complications or comorbidities; 5.no absolute contraindications to exercise; 6.not participating in any other scientific research; 7.scheduled to deliver at Guangdong Maternal and Child Health Hospital; 8.capable of conducting basic communication in Chinese.
Exclusion criteria
Exclusion criteria: 1.Patients undergoing in vitro fertilization (IVF), twin or multiple pregnancies, those with absolute or relative contraindications to exercise during pregnancy, individuals diagnosed with mental disorders such as anxiety disorder or depression prior to pregnancy; or those expected to be unable to complete follow-up visits (e.g., those planning to deliver outside their local area). 2.Absolute contraindications for exercise during pregnancy include: severe cardiac or respiratory diseases, severe preeclampsia/eclampsia, uncontrolled hypertension, severe thyroid disorders, uncontrolled type 1 diabetes mellitus, premature rupture of membranes, threatened preterm labor, persistent vaginal bleeding of unknown cause, placenta previa after 28 weeks of gestation, cervical insufficiency, severe anemia, fetal growth restriction, and multiple pregnancies (three or more fetuses). 3.Relative contraindications for exercise during pregnancy include: mild to moderate cardiac or respiratory diseases, history of recurrent miscarriage or preterm birth, and severe pathological obesity (BMI >= 35 kg/m^2).2Or combined metabolic abnormalities), malnutrition, or extremely low body weight (BMI <12 kg/m^2).2), twin pregnancies after 28 weeks of gestation, and unstable epilepsy conditions; absolute or relative exercise contraindications during pregnancy (e.g., severe anemia, hypertension, fetal growth restriction, extremely high/low BMI, epilepsy, hyperthyroidism, or prolonged sedentary behavior in pregnant women, requiring cautious exercise under medical evaluation); patients diagnosed with mental disorders such as anxiety or depression before pregnancy; and those expected to be unable to complete follow-up visits (e.g., those planning to deliver outside their local area).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pelvic Floor Surface Electromyography Assessment;Three-dimensional Pelvic Floor Ultrasound;POP-Q staging assessment;Manual evaluation of pelvic floor muscle strength;Incidence of postpartum anxiety and depression;Incidence of pelvic floor dysfunction during pregnancy and postpartum; | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurement of four lipid parameter;C-reactive protein, CRP;Placenta-Derived Mesenchymal Stem Cells;Umbilical artery S/D ratio;Infant and early childhood developmental behavior; | — |
Countries
China
Contacts
Guangdong Women and Children Hospital