Parkinson's disease
Conditions
Interventions
Lifestyle medicine intervention:Develop a lifestyle medicine prescription, including nutritional intervention, physical activity, stress management, sleep management, smoking cessation and alcohol res
Traditional treatment control group:Traditional treatment
Sponsors
Shanxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40 to 70 years old; 2. Patients with clinically confirmed or highly probable Parkinson’s disease who meet the Chinese Diagnostic Criteria for Parkinson’s Disease (2016); 3. In the on-phase of medication, with Hoehn-Yahr (H-Y) stage <= 2.5; 4. Able to cooperate well with lifestyle intervention measures; 5. The subjects and/or their legal representatives have a full understanding of the trial content, voluntarily sign the informed consent form, and agree to complete the trial in accordance with the protocol.
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed with Parkinsonism other than idiopathic Parkinson’s disease, or those with an unclear diagnosis; 2. A history of stroke or intracranial space-occupying lesions; 3. A history of ophthalmic diseases affecting eye movements; 4. Any neurological diseases or musculoskeletal injuries (such as fractures, stroke sequelae, etc.) that interfere with gait or balance, other than the motor symptoms of Parkinson’s disease; 5. Patients with mental illnesses or those unable to cooperate for other reasons (including but not limited to: dementia, a score of = 23 on the Mini-Mental State Examination); 6. Other circumstances: Uncontrollable factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Movement Disorder Society - Unified Parkinson's Disease Rating Scale(MDS-UPDRS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale;Hamilton Anxiety Rating Scale;Mini-Mental State Examination(MMSE);Functional Magnetic Resonance Imaging (fMRI);Parkinson’s Disease Sleep Scale-2(PDSS-2);Montreal Cognitive Assessment (MoCA);Activities of Daily Living, ADL;EyeKnow Neuromental Health Assessment;Quality of Life in Patients with Parkinson's Disease-39; | — |
Countries
China
Contacts
Public ContactBai Xue
Shanxi Provincial People's Hospital
Outcome results
None listed