Myasthenia
Conditions
Interventions
Group 1 (sarcopenia group): elderly patients who meet the diagnostic criteria of the Asian Working Group for Sarcopenia (AWGS) 2019:None
Group 2 (control group): healthy older adults matched for age and sex without sarcopenia:None
Sponsors
Hainan Provincial people's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. More than 60 years old; 2. No history of lower limb trauma or operation; 3. Barrier-free standing and walking; 4. Informed consent.
Exclusion criteria
Exclusion criteria: 1. Muscle-related diseases: myositis, myasthenia gravis, Parkinson's disease, stroke; 2. Seriously affecting muscle metabolic diseases: hyperthyroidism or hypothyroidism, malignant tumor, etc.; 3. Severe mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measure the muscle thickness of rectus femoris muscle under the condition of straightening and knee flexion 90 °(MT straight, MT bending);Measure the cross-sectional area of rectus femoris muscle under the condition of straightening and knee flexion 90 °(CSA straight, CSA bending);The microvascular blood flow velocities of rectus femoris muscle extension and knee flexion 90 °(MV straight, MV bending) were measured.;Measure the elastic modulus of the rectus femoris muscle under the condition of 90 °knee flexion and extension (E straight, E bending).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sex;age; height(cm); weight;5 sit-up test time(s);6m walking speed test time;Grip strength test(kg);Appendicularskeletalmusclemassindex,ASMI; | — |
Countries
China
Contacts
Public ContactWu Rinuan
Hainan Provincial people's Hospital
Outcome results
None listed