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A Study on the Sedative Effect of Dexmedetomidine Combined with Ciprofol in Breast Mass Resection

A Randomized Controlled Study on the Sedative Effect of Dexmedetomidine Combined with Ciprofol in Breast Mass Resection

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124108
Enrollment
Unknown
Registered
2026-05-07
Start date
2025-09-16
Completion date
Unknown
Last updated
2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Mass

Interventions

Low-dose Dexmedetomidine Group :Low-dose Dexmedetomidine
Normal Saline Control Group : Normal Saline

Sponsors

Suzhou Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1.Patients aged 25 to under 60 years; 2.ASA physical status classification of Grade I to II; 3.Patients who undergoing elective breast mass resection.

Exclusion criteria

Exclusion criteria: 1.Severe preoperative cardiovascular diseases, including NYHA functional classification Grade ? or higher, sinus bradycardia (heart rate 30.0 kg/m²; 6.Patients with glaucoma, myasthenia gravis, tachyarrhythmia, severe gastrointestinal obstruction or paralytic ileus, and those with hypersensitivity to atropine; 7.ASA physical status classification Grade ? or higher, and emergency surgery.

Design outcomes

Primary

MeasureTime frame
Ramsay Score at 10 Minutes After Drug Discontinuation;

Secondary

MeasureTime frame
MAP;HR;SPO2;Number of additional doses of ciprofol;Total dosage of cyclophenol;Wake-up time;Whether there was a motor response during skin incision;Laryngeal mask insertion;hypotension;bradycardia;Respiratory depression;Injection pain;Nausea and vomiting;Sleep quality on the night after surgery;Post-anesthesia care unit pain score;

Countries

China

Contacts

Public ContactLe Wang

Suzhou Municipal Hospital

741495980@qq.com+86 132 0519 9786

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 16, 2026