Stroke
Conditions
Interventions
Combined group:Brain-computer interface combined with modified constraint-induced movement therapy
Control group:modified constraint-induced movement therapy alone
Sponsors
Xuzhou Rehabilitation Hospital Affiliated to Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 75 years; 2.First-ever stroke; 3.Unilateral lesion with a disease duration of less than 6 months and stable vital signs; 4.Fulfillment of the training criteria for mCIMT in stroke patients: active wrist extension of the affected upper extremity exceeding 20°, active extension of the thumb and at least two additional fingers at the metacarpophalangeal and interphalangeal joints exceeding 10°, performed at least three times per minute ; and passive range of motion meeting the following requirements: shoulder flexion and abduction exceeding 90°, elbow extension exceeding 30°, and both forearm pronation and supination exceeding 45°; 5.Modified Ashworth Scale grade for flexor muscle tone in the upper limb <= II; 6.Mini-Mental State Examination score of 21 or higher, with intact consciousness and adequate cognitive function to cooperate with evaluation and treatment; 7.Absence of auditory or visual impairments.
Exclusion criteria
Exclusion criteria: 1.Presence of traumatic brain injury, progressive stroke, or subarachnoid hemorrhage with an unstable clinical condition; 2.Comorbid severe cardiac, hepatic, pulmonary, or renal insufficiency, malignancy, psychiatric trauma, or cognitive dysfunction; 3.Use of implanted electronic devices (such as cardiac pacemakers) or presence of metallic implants (such as stents); 4. Personal or family history of epilepsy; 5.Poor treatment compliance precluding completion of the trial; 6. Severe pain, sensory loss, hyperesthesia, or other sensory impairments affecting the hemiplegic limb.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Wolf Motor Function Test;modified Barthel Index; | — |
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment for Upper Extremity; | — |
Countries
China
Contacts
Public ContactWenjie Zhou
Xuzhou Rehabilitation Hospital Affiliated to Xuzhou Medical University
Outcome results
None listed