Application of High-Pressure Resistant Mini-Midline Catheters in Contrast-Enhanced Examinations for Patients with Difficult Venous Access

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600124080

Enrollment

Unknown

Registered

2026-05-07

Start date

2026-05-07

Completion date

Unknown

Last updated

2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Difficult intravenous access (DIVA)

Interventions

Experimental group:Insertion of high-pressure resistant mini-midline catheter

Control group:Insertion of high-pressure 20G peripheral intravenous catheter

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Age >=18 years old. 2.Requiring intravenous infusion therapy during hospitalization. 3.Having suitable veins in the upper extremities for catheter insertion, confirmed by ultrasound evaluation. 4.Meeting the diagnostic criteria for Difficult Intravenous Access (DIVA), requiring ultrasound-guided vascular access establishment. 5.Clinically indicated for contrast-enhanced CT or MRI examination, requiring rapid contrast agent injection via a high-pressure injector. 6.Providing written informed consent and voluntary participation in the study.

Exclusion criteria

Exclusion criteria: 1.Presence of infection, dermatitis, trauma or lymphedema at the catheter insertion site. 2.Known severe allergy to catheter materials (e.g., polyurethane) or dressings. 3.Confirmed or suspected catheter-related bloodstream infection (CRBSI) or deep venous thrombosis (DVT). 4.Severe coagulation dysfunction or thrombocytopenia; 5.Severe renal insufficiency with planned use of hypertonic contrast agent (which increases the risk of renal injury and may affect catheter selection). 6.Limbs on the ipsilateral side after radical mastectomy for breast cancer, or limbs with arteriovenous fistula. 7.Any other conditions deemed unsuitable for participation by the investigators.

Design outcomes

Primary

Measure	Time frame
Overall incidence of vascular access-related complications;	—

Secondary

Measure	Time frame
Vascular access-related cost data;One-time success rate of high-pressure contrast injection;First-attempt cannulation success rate;	—

Countries

China

Contacts

Public ContactWenrui SUN

The First Affiliated Hospital of Wenzhou Medical University

272207918@qq.com+86 577 55579482

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 16, 2026