Pancreatic cancer, liver metastasis, microbiota metabolism
Conditions
Interventions
Gold Standard:Pathological diagnosis
Index test:Puncture biopsy or surgical patholog,stool microbiome,
Sponsors
Henan Provincial People's Hospita,medical
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.age >= 18 and = 0 and <=2 points; 6. The expected survival period is = 3 months
Exclusion criteria
Exclusion criteria: 1. There are other malignant tumors in combination; 2. Expected survival time <3 months; 3. History of drug abuse or drug users; 4. Concurrent mental disorders that affect the treatment received; 5. Previous history of gastrointestinal surgery (such as subtotal gastrectomy, colectomy, etc., which may affect changes in intestinal microbiota); 6. Antibiotics have been used within the past month; 7. Unable to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient survival rate (relapse-free survival); | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal elastase-1 level;Serum cholecystokinin (CCK) expression level;Fecal microbiome differences;Symptom assessment (diarrhea, abdominal pain, indigestion, changes in bowel frequency); | — |
Countries
China
Contacts
Public ContactQin Tao
Henan Provincial People's Hospita,medical
Outcome results
None listed