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A comparative study of Transcervical Autologous Fat Injection versus Silicone Implant Thyroplasty for Improving Laryngeal Function in Patients with Unilateral Vocal Cord Paralysis

A comparative study of Transcervical Autologous Fat Injection versus Silicone Implant Thyroplasty for Improving Laryngeal Function in Patients with Unilateral Vocal Cord Paralysis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124074
Enrollment
Unknown
Registered
2026-05-07
Start date
2024-03-01
Completion date
Unknown
Last updated
2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vocal fold paralysis

Interventions

Thyroplasty type 1:1.Patients are placed in a supine position under cervical plexus anesthesia. A transverse incision is made on the neck skin to expose the thyroid cartilage. A window is created in t
Fat Injection :2.Autologous Fat Injection: Patients are placed in a supine position under general anesthesia. Approximately 5 ml of fat is harvested from the lower abdomen via an incision. The fat is

Sponsors

Guangdong Provincial People's hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years. 2. Patients with voice abnormalities who require surgical treatment. 3. Patients diagnosed with vocal cord paralysis via electronic laryngoscopy with a medical history of more than 9 months. 4. Patients with voice abnormalities identified by Voice Handicap Index (VHI) assessment and auditory subjective assessment. 5. Patients with or without swallowing aspiration or choking. 6. Patients who agree to participate in this trial and have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who do not wish to undergo surgical treatment. 2. Patients who cannot cooperate with laryngoscopy and voice assessment. 3. Patients with severe cardiopulmonary diseases who cannot tolerate surgery. 4. Patients with severe conditions who cannot take care of themselves in daily life. 5. Patients with a history of laryngeal surgery before this trial.

Design outcomes

Primary

MeasureTime frame
Voice handicap index;

Secondary

MeasureTime frame
laryngoscope;perceptual assessment;maximum phonation duration;acoustic analysis;

Countries

China

Contacts

Public ContactPingjiang Ge

Guangdong Provincial People's hospital

gepingjiang@gdph.org.cn+86 137 5175 3465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 16, 2026