Temporomandibular joint osteoarthritis
Conditions
Interventions
Modified digital occlusal splint group:Modified digital occlusal splint treatment worn at night for 6 months, combined with oral glucosamine hydrochloride 1500 mg/day for 3 months and health education
Conventional digital occlusal splint group:Conventional digital occlusal splint treatment worn at night for 6 months, combined with oral glucosamine hydrochloride 1500 mg/day for 3 months and health e
Glucosamine-only group:Oral glucosamine hydrochloride alone at 1500 mg/day for 3 months, combined with health education.
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adult patients aged 18 years or older; 2. Diagnosed with temporomandibular joint osteoarthritis (TMJOA) using DC/TMD diagnostic criteria and temporomandibular joint CBCT imaging examination; 3. Have not received any treatment related to temporomandibular joint disorders in the past 3 months; 4. Able to understand the study content, voluntarily participate in this study, and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of orthodontic treatment or orthognathic surgery; 2. Presence of severe periodontal disease affecting >=3 teeth; 3. History of cleft lip and palate or other diseases affecting craniofacial growth and development; 4. Suffering from rheumatoid arthritis or other systemic diseases; 5. Having psychological or psychiatric disorders that may affect study compliance or outcome evaluation; 6. Women who are planning pregnancy or are pregnant; 7. Refusal to participate in this study or inability to complete follow-up according to the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximum mouth opening; | — |
Countries
China
Contacts
Public ContactXiao Cen
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed