Knee osteoarthritis
Conditions
Interventions
contrast group:Sodium hyaluronate was injected into the knee cavity
intervention group:Concentrated growth factor was injected into the knee cavity
Sponsors
Yancheng First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Diagnosis of knee arthritis by standardized radiological assessment (i.e., standing anteroposteric and lateral X-ray views); 2. Kellgren-Lawrence Scale is I, II, or III, Visual Analogue Scale (VAS) pain score Moderate pain (>4); 3. Age >18; 4. Subject understands and signs informed consent.
Exclusion criteria
Exclusion criteria: 1. Kellgren-Lawrence Rating Scale IV; 2. Female patients who are pregnant, nursing or trying to become pregnant; 3. BMI>30; 4. Previous history of knee fracture surgery, knee instability and other diseases; 5. 3 History of intraregional injection or periarticular invasive treatment and surgery within the past month; 6. Autoimmune diseases such as rheumatoid arthritis and ankylosing spondylitis; 7. Past or present malignant tumors; 8. Suffers from neuropathic joint disease, hepatitis B and other diseases; 9. Suffering from HIV and other immunodeficiency diseases; 10. Suffering from cerebral hemorrhage, severe pneumonia, multiple organ dysfunction and other serious diseases; 11. Severe anemia; 12. Past or present mental or psychological illness; 13. Active infection in other parts of the body; 14. Patients with diabetes whose FBG exceeds 8mmol/L and is still poorly controlled after taking medicine; 15. Currently using anticoagulant drugs; 16. Patients who cannot follow up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Arthritis Index, WOMAC; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale, VAS ;International Knee Documentation Committee; | — |
Countries
China
Contacts
Public ContactSun Guan
Yancheng First People's Hospital
Outcome results
None listed