ICU-acquired weakness
Conditions
Interventions
Group A:The UG-NMES group received ultrasound-guided neuromuscular electrical stimulation
Group B1:Receive traditional neuromuscular electrical stimulation at 40mA
Group B2:Receive traditional neuromuscular electrical stimulation at 50mA
Sponsors
The Army Specialized Medical Center of the People's Liberation Army of China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18–80 years; 2.Having been admitted to the ICU for more than 48 hours; 3.Meet the diagnostic criteria of ICU-AW (Medical Research Council (MRC) muscle strength score < 48 points, and excluding muscle weakness caused by other reasons); 4.The patient or the family member signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe heart diseases (such as severe arrhythmia, decompensated heart failure); 2. Implantation of a cardiac pacemaker or defibrillator; 3. Skin damage, infection or allergy, making it impossible to place the electrode patches; 4. Pregnant or lactating women; 5. Expected survival period > 3 months; 6. Comatose patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle Function Improvement (Measured by Musculoskeletal Ultrasound Structural Parameters); | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline signs and symptoms;Laboratory Safety Assessment;Muscle Function Improvement;Physical examination and vital signs;Serum inflammatory factors; | — |
Countries
China
Contacts
Public ContactZhen Wang
The Army Specialized Medical Center of the People's Liberation Army of China
Outcome results
None listed