Epstein-Barr virus (EBV)-associated gastric cancer with concurrent Helicobacter pylori (HP) infection
Conditions
Interventions
EBV mono-infection group:None
HP mono-infection group:None
EBV/HP co-infection group:None
Control Group:None
Sponsors
The Third Affiliated Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Histopathologically confirmed gastric cancer in accordance with the WHO Classification of Tumours of the Digestive System (5th edition, 2019); 2. EBV-positive status confirmed by EBER in situ hybridization; 3. HP infection confirmed by urea breath test or histological examination; 4. Age >=18 years; 5. Complete and traceable medical records.
Exclusion criteria
Exclusion criteria: 1. Presence of concurrent malignancies or severe systemic diseases (e.g., advanced heart failure, end-stage renal disease); 2. EBV or HP infection status not determined; 3. Prior neoadjuvant chemotherapy or radiotherapy before surgery; 4. Incomplete medical documentation.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Objective Response Rate (ORR);Progression-Free Survival (PFS); | — |
Primary
| Measure | Time frame |
|---|---|
| Overall Survival; | — |
Countries
China
Contacts
Public ContactJianning Chen
The Third Affiliated Hospital Sun Yat-sen University
Outcome results
None listed