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Effectiveness of a Minimally Invasive Combined Periodontal-Endodontic Technique for the Precision Treatment of Deep Subgingival Caries on the Distal Cervical Aspect of Mandibular Second Molars

Effectiveness of a Minimally Invasive Combined Periodontal-Endodontic Technique for the Precision Treatment of Deep Subgingival Caries on the Distal Cervical Aspect of Mandibular Second Molars

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124049
Enrollment
Unknown
Registered
2026-05-06
Start date
2026-05-07
Completion date
Unknown
Last updated
2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental caries

Interventions

Control group:Class II cavity restoration with composite resin
Experimental group:Composite resin restoration during flap surgery

Sponsors

Shanghai Stomatological Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-65 years; 2. At least one mandibular second molar with deep subgingival distal cervical caries caused by an impacted third molar, and the impacted third molar has been extracted for >=4 weeks; 3. Intact distal marginal ridge of the affected tooth; 4. Normal pulp vitality of the affected tooth; 5. Patients who understand the study and voluntarily sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Distance from coronal margin of the cavity to distal marginal ridge = 5mm apical to the cementoenamel junction; 3. Abnormal pulp vitality, diagnosed pulpitis or periapical periodontitis; 4. Uncontrolled periodontitis; 5. Mouth opening <= 25mm; 6. Uncontrolled severe systemic diseases or contraindications to local anesthesia; 7. Severe osteoporosis or long-term bisphosphonate use; 8. Pregnancy, lactation, or planned pregnancy within 2 years; 9. Inability to comply with treatment or follow-up; 10. Investigator's judgment of inappropriateness for participation.

Design outcomes

Primary

MeasureTime frame
success rate;

Secondary

MeasureTime frame
retention rate;

Countries

China

Contacts

Public ContactLiu Bin

Shanghai Stomatological Hospital

pizzanet@163.com+86 138 1759 0835

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 16, 2026