Coronary heart disease
Conditions
Interventions
Observation group:none
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18 - 90 years old; 2. This study refers to the "2024 ESC Guidelines for the Management of Chronic Coronary Syndrome" [19] and the "Global Definition of Myocardial Infarction" (2018) [20]. The diagnosis of coronary heart disease must meet the following criteria: any one of the following: (1). CTCA/ICA shows lumen stenosis >= 50%;(2). Previous MI or revascularization (PCI/CABG); (3). Typical angina symptoms + ischemic evidence: 1). Clinical manifestations Mainly manifested as exertional angina, with the following characteristics: Location of chest pain: behind the sternum or in the precordial area, which may radiate to the left shoulder and the inner side of the left arm;Nature of pain: a sense of oppression, tightness, or suffocation, lasting for several minutes to over ten minutes;Inducing factors: physical activity, emotional excitement, overeating, cold, etc;Relief methods: can be rapidly relieved by rest or sublingual administration of nitroglycerin. 2). Ischemic evidence (satisfying any one of the following) Electrocardiogram: resting electrocardiogram may be normal, but during angina attack, ST segment depression or T wave inversion may be observed. Echocardiography through the chest: Segmental abnormality of ventricular wall motion;Stress echocardiography: Abnormal local systolic thickening of the ventricular wall during stress;Computed tomography perfusion imaging: Manifested as low-density areas on the images. 3. There is no gender restriction for the subjects; 4. Voluntary participation in this study and signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Vulnerable groups, including those with mental illness, cognitive impairment, critically ill patients, women in pregnancy, lactation or with positive pregnancy test, and those with communication and comprehension difficulties that prevent them from completing follow-up visits, etc; 2. Congenital heart disease, cardiomyopathy; 3. Patients with a history of moderate or severe valvular disease; 4. Patients with malignant tumors and an expected survival of less than 2 years; 5. History of drug or alcohol abuse within the last 12 months; 6. Hemodynamic instability requiring mechanical assistance such as IABP or ECMO.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The first MACE (A composite event of Cardiovascular death, non-fatal MI, non-fatal stroke); | — |
Secondary
| Measure | Time frame |
|---|---|
| Medication intake situation;Auxiliary examination;Symptoms and signs;Blood biochemistry, blood routine, coagulation factors, inflammatory factors, myocardial injury markers, BNP/NT-proBNP, urine routine;General demographic data;Medical history, comorbidities; | — |
Countries
China
Contacts
Public ContactWei Wang
The Second Affiliated Hospital of the Army Medical University
Outcome results
None listed