Osteoarthritis (OA)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients undergoing primary unilateral total knee arthroplasty; 2.Aged 18 to 80 years; 3.American Society of Anesthesiologists (ASA) physical status classification grade I–III; 4.Preoperative Barthel Index = 60 points, with basic self-care ability in daily life;
Exclusion criteria
Exclusion criteria: 1.Patients undergoing simultaneous bilateral total knee arthroplasty or knee revision arthroplasty; 2.Patients with preoperative neuromuscular diseases of lower extremities or severe knee deformities that interfere with muscle strength and functional assessment; 3.Patients with severe dysfunction of major organs including heart, lung, liver and kidney who cannot tolerate early rehabilitation training; 4.Patients with allergy to local anesthetics; 5.Patients with coagulation disorders unsuitable for nerve block procedures; 6.Patients with mental disorders or cognitive impairment who cannot cooperate with functional evaluation and follow-up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Barthel Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rest and dynamic Numerical Rating Scale (NRS) pain scores;postoperative analgesic consumption;quadriceps muscle strength (MRC scale);time to first postoperative ambulation;postoperative readmission rate;length of hospital stay;incidence of postoperative complications;total hospitalization expenses; | — |
Countries
China
Contacts
Suining Central Hospital