Prostate Cancer
Conditions
Interventions
Ropivacaine TFPB Group (T Group):0.3% Ropivacaine 25mL injected into the transversus abdominis plane
Esmirtamine Combined with Ropivacaine TFPB Group (ET Group):0.3% Ropivacaine combined with 0.2mg/kg Esmirtamine, total 25mL injected into the transversus abdominis plane
Control Group (C Group):0.9% Normal Saline 25mL injected into the transversus abdominis plane
Sponsors
Ningbo Medical Center Li Huili Hospital
Eligibility
Sex/Gender
Male
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for laparoscopic radical prostatectomy; 2. Male, aged 60 to 85; 3. American Society of Anesthesiologists (ASA) classification I-III; 4. No abnormal coagulation function; 5. No neurogenic bladder; 6. No research on drug allergy. 7. Subjects who agreed to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Severe visual and hearing disorders; 2. Those who are unable to cooperate to complete the test; 3. Serious diseases of the heart, brain, lungs, liver and kidneys; 4. History of drug abuse or addiction; 5. There were mental disorders and cognitive impairments before the operation; 6. History of local anesthetic allergy; 7. Infection at the puncture site. 1) Occurrence of serious adverse events during the perioperative period (massive hemorrhage, deterioration of underlying diseases, and postoperative admission to the ICU, etc.); 2) The TFPB operation failed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and grading of CRBD and visual analog scale (VAS) pain scores at multiple time points within 24 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and grading of CRBD;Opioid consumption;Number of patient-controlled analgesia (PCA) uses and rescue analgesia requirements postoperatively;Early postoperative enhanced recovery after surgery (ERAS) related indicators; | — |
Countries
China
Contacts
Public ContactXu Wenfei
Ningbo Medical Center Li Huili Hospital
Outcome results
None listed