Biliary and Pancreatic Diseases
Conditions
Interventions
Remimazolam Group (Group R):Anesthesia Induction (Group R): Administer sufentanil 0.1–0.15 µg/kg intravenously, followed by remimazolam 0.25 mg/kg (>30 seconds), and then cisatracurium 0.15 mg/kg via
Ciprofol Group (Group C):Anesthesia Induction (Group C): Administer sufentanil 0.1–0.15 µg/kg intravenously, followed by ciprofol 0.4 mg/kg (>30 seconds), and then cisatracurium 0.15 mg/kg via slow in
Sponsors
The Affiliated Hospital of North China University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients who are scheduled to undergo elective endoscopic retrograde cholangiopancreatography (ERCP) under general anesthesia with endotracheal intubation. 2.Age 18 to 80 years, inclusive. 3.American Society of Anesthesiologists (ASA) Physical Status Class I-III. 4.Patient (or legally authorized representative) is willing and able to provide written informed consent.
Exclusion criteria
Exclusion criteria: (1) allergy to study drugs; (2) foreseeable history of difficult airway and severe respiratory diseases (acute respiratory infection, acute exacerbation of COPD, uncontrolled asthma, etc.); (3) severe heart, liver and kidney dysfunction; (4) pregnant or lactating women; (5) hearing/vision/language disorders affecting communication; (6) long-term use of analgesics or psychotropic drugs for chronic pain; (7) not fit according to the investigator's judgment (inability to cooperate with mental illness, history of alcohol or drug abuse, etc.). (8) patients with postoperative tube in ICU
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Pressure;Heart Rate;Oxygen Saturation;Area Under the Curve of Hypotension (Hypotension AUC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 (QoR-15);Time to Emergence;Incidence of Adverse Events; | — |
Countries
China
Contacts
Public ContactLiu Tiejun
The Affiliated Hospital of North China University of Science and Technology
Outcome results
None listed