Intrahepatic Cholestasis of Pregnancy (ICP)
Conditions
Interventions
Group A1:None
Group A2:None
Group B:None
Sponsors
Women and Children's Hospital of Ningbo University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Pregnant women with regular prenatal care between 28 and 32 weeks of gestation in our hospital. 2. All participants had good eating habits, no history of chronic constipation, no history of acute or chronic gastrointestinal inflammation, and no history of gastrointestinal surgery. 3. No use of any antibiotics (oral, intravenous, or vaginal) or probiotics (before the first stool sampling) within nearly 30 days before sampling; 4. There were no significant differences in age, parity, weight and diet between the two groups of subjects, and all of them were singleton pregnancies
Exclusion criteria
Exclusion criteria: History of gestational diabetes mellitus, autoimmune diseases, gestational hypertension, malignant tumors, etc. (The presence or absence of the above diseases is determined at the time of enrollment.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total bile acids, TBA;Serum alanine aminotransferase (ALT);Serum aspartate aminotransferase (AST);Pregnancy comorbidities/complications,;Gestational age at termination;Mode of delivery;Neonatal outcomes;Postpartum hemorrhage.;Maternal clinical symptoms; | — |
Countries
China
Contacts
Public ContactXiaobo He
Women and Children's Hospital of Ningbo University
Outcome results
None listed