Immediate implant restoration in the aesthetic area of the anterior teeth
Conditions
Interventions
Trial Group:RuiZhi BioRes Customized Implant Restoration Protocol (including digital surgical guide, temporary prosthesis design, temporary abutments, and other accessories)
Sponsors
Stomatological Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily cooperate with this research and sign the informed consent form for the research; 2. Gender is not limited. Age range: 18 years old to 60 years old. Good medical compliance. 3. The affected tooth that cannot be retained is located in the aesthetic zone of the maxillary anterior teeth: that is, 13/-23/, and it is a single affected tooth. 4. Systemically healthy patients (American Society of Anesthesiologists - ASA Class I and II: With mild complications other than surgical diseases and sound functional compensation); 5. The entire mouth does not have periodontal disease or the periodontal condition is in the periodontal maintenance stage (plaque index < 20%, probing bleeding score < 10%), and there is no gingival recession. 6. According to the preoperative CBCT assessment, even if there is a potential bone fenestration during the operation, it should be limited to the apical one-third of the alveolar cavity.
Exclusion criteria
Exclusion criteria: 1. Participate in other clinical research simultaneously; 2. Patients with contraindications for conventional dental implant surgery or uncontrolled systemic diseases, including: (1) Severe systemic diseases: 1) Hypertension with systolic blood pressure (high pressure) > 150mmHg or diastolic blood pressure (low pressure) > 90mmHg. 2) Uncontrolled diabetes: fasting blood glucose >= 7.0mmol/L or glycated hemoglobin (HbA1c) > 7%. 3) Heart disease (cardiac function grade 3-4), or symptoms such as orthopnea and lower extremity edema. 4) Heart and lung diseases, heart failure patients. 5) Cardiovascular and cerebrovascular diseases (angina pectoris, myocardial infarction, cerebral infarction within half a year, or frequent recent angina pectoris attacks). 6) Third-degree or second-degree type II atrioventricular block, bifascicular block, Adams-Stokes syndrome. 7) Heart valve disease. 8) Acute hepatitis (causing severe liver damage). 9) Severe asthma, severe pharyngitis, severe depression. 10) Severe hyperthyroidism: pulse > 100 beats per minute, basal metabolic rate > 20%. 11) Blood diseases: hemophilia, leukemia and other bleeding disorders, or patients with coagulation disorders due to anticoagulant drugs, INR > 3 or clinically significant abnormal values in the seven coagulation tests. (2) Long-term use of the following drugs: 1) Patients who have received injections and large oral doses of bisphosphonates for the prevention of bone metastasis and treatment of osteoporosis. 2) Patients with joint necrosis due to the use of hormone drugs (typical case: SARS patients). 3) Patients treated with long-term adrenal cortical hormones. (3) AIDS, syphilis and drug addicts. (4) Patients whose bodies cannot tolerate surgery due to other systemic diseases. (5) Patients with pathological changes in the gums and surrounding hard tissues. 3. Those with acute or severe infections and a white blood cell count greater than 10^9/L; 4. Abnormal occlusal relationships or bad occlusal habits exist in the proposed implantation area, which may cause traumatic absorption of the soft tissues around the implant and lead to surgical failure. Oral mucosal lesions There is severe soft tissue inflammatory lesion in the area of missing teeth. Limited mouth opening; 5. The tooth socket is classified as type I: the labial soft tissue is intact, but the buccal plate is partially missing after tooth extraction; or type III: both the labial soft and hard tissues are significantly reduced after tooth extraction. 6. History of drug allergy: Severe allergic reactions to various drugs that will be used during and after the operation, including anesthetic drugs, anti-inflammatory and analgesic drugs, etc. 7. Women who are pregnant, menstruating or breastfeeding; 8. Those with uncontrolled periodontal disease or poor oral hygiene habits that cannot be improved (probing depth > 4mm, BOP > 10%); 9. Severe smokers (more than 10 cigarettes per day); 10. Patients with other systemic diseases that may affect wound healing after assessment, such as chronic tuberculosis, hypothyroidism, autoimmune diseases, etc. 11. History of malignant tumors, with a history of radiotherapy or chemotherapy for malignant tumors in the past 5 years; 12. Those who the researcher deems unsuitable to participate in this clinical trial for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Marginal Bone Levels, MBL; | — |
Secondary
| Measure | Time frame |
|---|---|
| Jemt' spapillary presence index, PPl;Implant success rate;modified Sulcus Bleeding Index, mBI;Visual Analogue Scale, VAS;Pink Esthetic Score (PES) and White Esthetic Scores (WES); | — |
Countries
China
Contacts
Public ContactGuo Zehong
Stomatological Hospital of Southern Medical University
Outcome results
None listed