AIDS combined with malignant tumor
Conditions
Interventions
Observation group:None
Sponsors
The Third People's Hospital of Shenzhen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years, no gender restriction; 2.Confirmed diagnosis of HIV infection according to the Chinese AIDS Diagnosis and Treatment Guidelines (2024 Edition); 3.Histopathologically or cytopathologically confirmed diagnosis of malignant tumors (including solid tumors or hematologic malignancies); 4.Currently receiving or planning to receive standard antineoplastic therapy combined with antiretroviral therapy; 5.Expected survival >=3 months; 6.Willing to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Participation in other interventional clinical studies within 30 days prior to enrollment; 2.Pregnant or breastfeeding women; 3.Other conditions deemed by the investigator as unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma concentrations of antineoplastic and antiretroviral drugs;Pharmacokinetic parameters (AUC, Cmax, Cmin, CL, etc.); | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective response rate;Progression-free survival;Incidence and severity of adverse reactions; | — |
Countries
China
Contacts
Public ContactLiu Hu
The Third People's Hospital of Shenzhen
Outcome results
None listed