stroke
Conditions
Interventions
Cerebellum + M1 group:Cerebellum + M1iTBS
M1 group:M1iTBS
Control group:iTBS stimulation with sham stimulus
Sponsors
Peking University Shougang Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of the 2023 Clinical Management Guidelines for Ischemic Cerebrovascular Diseases of the Chinese Stroke Association, and whose diagnosis has been confirmed through intracranial CT or MRI examination, and who have lower limb motor dysfunction; 2. Patients with primary unilateral cerebral infarction or cerebral hemorrhage, accompanied by residual unilateral limb hemiparesis; 3. Patients aged 45-70 years old, with a disease duration of 1-6 months; 4. Standing balance >= 1 level, and able to complete at least 10 meters of walking with assistance; 5. Patients voluntarily participate and cooperate to complete the treatment, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Have a history of epilepsy or are currently taking drugs that lower the threshold of epilepsy; 2. Have metal implants in the body (such as cardiac pacemakers, cochlear implants, intracranial metal clips, etc.); 3. Have severe cognitive impairment or aphasia and are unable to cooperate; 4. Have other diseases that cause abnormal walking (such as Parkinson's disease, spinal cord injury, lower limb fractures, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (Fugl-Meyer Assessment of Lower Extremity Score;Gait cycle;Double support phase; | — |
Secondary
| Measure | Time frame |
|---|---|
| (Berg Balance Scale Score;Modified Barthel Index Score;Modified Ashworth Scale Score;Functional Ambulation Category Scale Score;Motor Evoked Potential;Central Motor Conduction Time;Resting Motor Threshold;leg speed;stride frequency;stride; | — |
Countries
China
Contacts
Public ContactLiang Wu
Peking University Shougang Hospital
Outcome results
None listed