gout
Conditions
Interventions
Experimental group:IL-1 inhibitor injection, specification: 200mg/bottle, single subcutaneous injection.
Control group:Conventional treatment regimen (one of the following options chosen by the researcher based on the "Chinese Gout Diagnosis and Treatment Guidelines"): non-steroidal anti-inflammatory dru
colchicine
oral glucocorticoids (such as prednisone). Doses and treatment durations were standardized.
Sponsors
Quanzhou First Hospital Affiliated to Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-70 years old; 2.meeting the ACR/EULAR gout classification criteria for acute attack.
Exclusion criteria
Exclusion criteria: 1. Active infectious phase; 2. Severe liver and kidney dysfunction; 3. Allergy to components of the study drug; 4. Long-term use of sedatives or medications affecting sleep rhythms; 5. Presence of other uncontrolled inflammatory arthritis or sleep apnea syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients with recurrent gout; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale;PSQI;Joint swelling and pain score;hs-CRP;IL-1ß;ESR; | — |
Countries
China
Contacts
Public ContactZhang Yi
Quanzhou First Hospital Affiliated to Fujian Medical University
Outcome results
None listed