Breast mass
Conditions
Interventions
Tegelitide Group (T Group):Fumaric Tegelitide 20µg/kg, intravenous slow push
Sufentanil Group (S Group):Sufentanil 0.2µg/kg, intravenous slow push
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Scheduled for elective breast lesion resection (male or female); 2. Age: 18–64 years; 3. ASA physical status classification: I–II; 4. BMI: 18.5–28 kg/m^2; 5. Clear consciousness and normal communication ability; 6. Willing to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiovascular or cerebrovascular diseases, hepatic or renal dysfunction, or psychiatric disorders; 2. Patients with a history of chronic pain or long-term use of analgesic medications; 3. Known allergy to analgesic drugs; 4. History of difficult airway (e.g., obstructive sleep apnea syndrome), severe respiratory depression (e.g., oxygen saturation <90%), or a history of acute or severe bronchial asthma; 5. Known or suspected gastrointestinal obstruction, including paralytic ileus; 6. Other conditions deemed by the investigator to make the patient unsuitable for participation in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative and postoperative adverse reactions;Postoperative 6-hour resting NRS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24-hour postoperative QoR-15 score;Postoperative sleep quality;Hemodynamic parameters at various intraoperative time points (before induction T0, after induction T1, at skin incision T2, 5 minutes after surgery start T3, at end of surgery T4);Incidence of rescue analgesia and rescue antiemesis within 24 hours postoperatively;Time to awakening after discontinuation of anesthetics; | — |
Countries
China
Contacts
Public ContactLiu Huafeng
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed