Induction phase hypotension
Conditions
Interventions
Case series:None
Sponsors
Guangdong Second Provincial General Hospital (Guangdong Provincial Emergency Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 - 65 (excluding those with dulled pressure reflex caused by arteriosclerosis). 2. A scheduled general anesthesia surgery is planned. 3. ASA Classification I - II. 4. Preoperatively agree to wear a Holter monitor and sign the informed consent form. 5. Surgical indications require radial artery puncture catheterization for pressure measurement (such as major abdominal surgery, thoracic surgery, spinal surgery, etc.).
Exclusion criteria
Exclusion criteria: 1. Arrhythmia: Persistent atrial fibrillation, frequent premature ventricular/atrial contractions (>5 times/min), pacemaker recipients (interfering with HRV analysis). 2. Interfering medications: Long-term use - receptor blockers (Beta-blockers), antiarrhythmic drugs, sympathetic/parasympathetic agents. (Note: Long-term use of SSRI/SNRI antidepressants cannot be ruled out, but it should be recorded). 3. Autonomic neuropathy: a serious complication of diabetes (such as diabetic foot, confirmed autonomic neuropathy). 4. Airway/Reflux Risk: Difficult airway or patients with a full stomach (unable to perform standard slow induction). Baseline Hypotension: Baseline SBP < 90 mmHg upon admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum blood pressure drop during induction period;Cardiovascular Coupling Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total load of vasoactive drugs;Incidence of severe hypotension; | — |
Countries
China
Contacts
Public ContactYuchao Wang
Guangdong Second Provincial General Hospital (Guangdong Provincial Emergency Hospital)
Outcome results
None listed