Anxiety
Conditions
Interventions
Group Remimazolam:Anesthesia was induced and maintained using remimazolam.
Induction: remimazolam 0.15–0.3 mg/kg + sufentanil 0.3–0.5 µg/kg + cisatracurium 0.15 mg/kg
Maintenance: remimazolam 0.3–1.5
Group propofol:Anesthesia was induced and maintained with propofol.
Induction:Propofol 1.5–2.5 mg/kg + Sufentanil 0.3–0.5 µg/kg + Cisatracurium 0.15 mg/kg
Maintenance:Propofol 4–12 mg/kg/h + Remifenta
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.No surgical contraindications and undergoing thyroidectomy. 2.ASA physical status Grade I-III. 3.Aged 18 to 65 years. 4.Female gender. 5.Voluntary participation in this study
Exclusion criteria
Exclusion criteria: 1.History of alcoholism, drug addiction, or mental illness(patients taking long-term anxiolytics, antidepressants, and sedative-hypnotics). 2.History of drug allergy. 3.Patients with nausea, vomiting, gastroesophageal reflux, delayed gastric emptying, pyloric obstruction, etc. 4.Complicated with severe cerebral, cardiac, pulmonary, hepatic, or renal diseases. 5.Severe sensory deficits (e.g., visual or hearing impairment) or other conditions that prevent normal communication with investigators and thus affect evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of anxiety;Recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety Score; pain score;Recovery quality; Adverse events;Recovery quality;Sleep quality;Hemodynamics;Extubation time; | — |
Countries
China
Contacts
Public ContactYoubo Zuo
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed