Non-Suicidal Self-Injury
Conditions
Interventions
Non-suicidal Self Injury Group:This study is an observational study and does not involve any intervention.
Health Control Group:This study is an observational study and does not involve any intervention.
Sponsors
Shanghai Pudong New Area Mental Health Center (Mental Health Center Affiliated with Tongji University)
Eligibility
Sex/Gender
All
Age
11 Years to 19 Years
Inclusion criteria
Inclusion criteria: Non-suicidal Self-Injury (NSSI) Group: 1. Assessed by two psychiatrists with intermediate-level or higher qualifications using the Self-Injurious Thoughts and Behaviors Interview (SITBI, Chinese version), and meeting the NSSI diagnostic criteria listed in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) (NSSI occurring on >=5 days within the past 12 months, with self-injury behaviors primarily motivated by non-suicidal intent); 2. Aged 11–19 years, right-handed; 3. Possess the cognitive ability to complete structured interviews and self-report questionnaires, and be able to follow research instructions to complete MRI scanning procedures; 4. No contraindications for MRI scanning; no history of modified electroconvulsive therapy, medication, or psychotherapy/counseling within the past 3 months; 5. Informed consent obtained from the participant and their guardian; voluntary participation. Health Control Group (HC): 1. Aged 11–19 years, right-handed, matched with the NSSI group in terms of age, gender, and educational level; 2. Confirmed via the SITBI interview to have no lifetime history of NSSI, suicidal ideation, plans, or behaviors; 3. Confirmed via the Mini-International Neuropsychiatric Interview (MINI) to have no history of past or current psychiatric disorders and no significant psychiatric symptoms in the past month; 4. Possess the cognitive ability to complete structured interviews and self-report questionnaires, and be able to follow study instructions to complete MRI scanning procedures; 5. Informed consent obtained from the participant and their guardian; voluntary participation.
Exclusion criteria
Exclusion criteria: 1. A current or past diagnosis of a severe mental disorder, such as schizophrenia, schizotypal disorder, schizoaffective disorder, delusional disorder, or bipolar disorder, according to DSM-5 criteria; 2. A mental disorder caused by a physical medical condition or by the use of psychoactive substances; 3. Symptoms caused by substance abuse; 4. Individuals with traumatic brain injury, epilepsy, or other known organic central nervous system disorders; 5. Individuals who have continuously taken antipsychotics, antidepressants, mood stabilizers, or similar medications for more than 2 weeks within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain imaging markers;NSSI trait indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Psychological trait indicators; | — |
Countries
China
Contacts
Public ContactFazhan Chen
Shanghai Pudong New Area Mental Health Center (Mental Health Center Affiliated with Tongji University)
Outcome results
None listed