Urinary calculi
Conditions
Interventions
OFA -PNB group:Opioid free anesthesia scheme (opioid free anesthesia + bilateral pudendal nerve block)
OBA group:General anesthesia with conventional opioids and laryngeal mask airway ventilation
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Male, aged 18-65 years, American Society of anesthesiologists (ASA) class I-III; 2.Body mass index (BMI) 18-28 kg/m^2; 3.Planned to undergo transurethral ureteral lithotripsy; 4.There was no severe cardiopulmonary dysfunction and normal coagulation function according to preoperative evaluation; 5.Clearly understand the experimental process and voluntarily participate, and sign the informed consent;
Exclusion criteria
Exclusion criteria: 1.Allergic to study medication; 2.Severe cardiac, hepatic and renal dysfunction; 3.History of mental illness or cognitive impairment; 4.Infection of puncture site; 5.Have a history of poorly controlled or untreated hypertension (resting systolic blood pressure > 180mmhg, diastolic blood pressure > 100mmhg); 6.High intraocular pressure (glaucoma) or penetrating ocular trauma; 7.The patient had sick sinus syndrome, heart rate <50 beats / min, and more than second degree atrioventricular block without pacemaker; 8.Parkinson's disease, Alzheimer's disease, epilepsy, long-term use of hypnotic sedatives; 9.History of chronic pain (defined as pain lasting or recurring for more than 3 months), preoperative use of analgesics; 10.Inability to communicate effectively or refusal to participate in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total score of the 15 item quality recovery scale (qor-15) 24h after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality scores and anxiety and depression scores 1 day before operation and 1, 3, and 7 days after operation;Incidence and severity of postoperative CRBD;Patient satisfaction score 24 hours after operation;Incidence of intraoperative hemodynamic adverse events;Time of first spontaneous urination, time of first spontaneous ambulation, incidence of nausea and vomiting, use of antiemetics, length of hospital stay;Recovery quality score at 48h after operation;Length of stay and hospitalization expenses;Incidence of adverse events of nerve block operation;PACU stay time and postoperative laryngeal mask removal time;Complications from leaving PACU to 48 hours after operation;Incidence of hypotension after induction;Complications in PACU; | — |
Countries
China
Contacts
Public ContactZhang Yang
The First Affiliated Hospital of Nanchang University
Outcome results
None listed