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Fibrin glue versus Cyanoacrylate glue in the management of frank or impending corneal perforation: A Randomized Control Trial

Fibrin glue versus Cyanoacrylate glue in the management of frank or impending corneal perforation: A Randomized Control Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123792
Enrollment
Unknown
Registered
2026-04-29
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal perforation

Interventions

Fibrin glue group and cyanoacrylate glue group:Fibrin and cyanoacrylate glue

Sponsors

King Edward Medical University/ Mayo Hospital, Lahore
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-85 years 2. Severe corneal thinning or perforation of size 3mm or less

Exclusion criteria

Exclusion criteria: 1. Previous surgical intervention for corneal thinning or perforation such as conjuctival flap, tectonic graft, amniotic membrane graft. 2. Severe thinning or perforation in a corneal graft (keratoplasty).

Design outcomes

Primary

MeasureTime frame
Efficacy of glue application (defined as intact globe and negative Seidel test at 1 month post-application);—

Secondary

MeasureTime frame
Visual acuity;Defect size;Seidel test result;Number of glue applications;Need for surgical intervention;—

Countries

Pakistan

Contacts

Public ContactAIMEN QAMAR KHAN

King Edward Medical University/ Mayo Hospital, Lahore

hijabkhan411@gmail.com+92 307 0607964

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026