Postoperative infection-related complications
Conditions
Interventions
Etoimidate Group:During general anaesthesia, intravenous anaesthesia was administered using etomidate.
Propofol group:During general anaesthesia, propofol is administered intravenously as the anaesthetic agent.
Sponsors
Yongchuan Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Elective surgery, to be performed under general anaesthesia with endotracheal intubation. Patients aged 18–75 years with an ASA II–III. 2.The anticipated duration of the procedure is not expected to exceed three hours. Significant blood loss and the need for transfusion therapy are not anticipated. 3.The patient and their family members were fully informed about the research content and voluntarily participated in and cooperated with the study.
Exclusion criteria
Exclusion criteria: 1.Patients with combined immune disorders or undergoing immunotherapy, or currently receiving radiotherapy and chemotherapy; 2.Concurrent haematological disorders or haematopoietic dysfunction, with abnormal neutrophil counts and percentage distribution; 3.malignant tumour patients; 4.Patients with evident systemic or localised infection; 5.Patients requiring high-dose corticosteroids during anaesthesia and surgery;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Phagocytic function;degranulation functionreactive ;oxygen species production;extracellular domain shedding; | — |
Countries
China
Contacts
Public ContactShouyong Wang
Yongchuan Hospital of Chongqing Medical University
Outcome results
None listed