Refractory chronic cough
Conditions
Interventions
Refractory Chronic Cough Group:None
Non refractory chronic cough group:None
Sponsors
Tongji Hospital of Tongji University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >18 years, any sex; 2. Cough as the sole or predominant symptom, with a duration of >8 weeks; 3. No significant abnormalities on chest CT; 4. FEV1/FVC ratio >70% and FEV1 % predicted >80%; 5. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Current smoking or smoking cessation for less than 2 years; 2. Pregnancy or lactation; 3. History of acute upper respiratory tract infection within the past 8 weeks; 4.Intravenous or oral use of glucocorticoids within the past 4 weeks; 5.Any disease of the hypothalamus, pituitary gland, or adrenal glands; 6. Severe cardiac insufficiency, severe hepatic or renal dysfunction, mental or cognitive impairment, hearing or communication disorders, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum cortisol;Salivary cortisol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Scale scoring;Blood IL-6, IL-1ß, TNF-a, CRP; | — |
Countries
China
Contacts
Public ContactYu Li
Tongji Hospital of Tongji University
Outcome results
None listed