Sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients in the cohort who have lived in the community for more than 6 months and are 65 years or older (regardless of gender); 2. Fully conscious, able to communicate with observers and community doctors, possess cognitive judgment ability, and can cooperate with measurements; 3. Able to walk independently and complete mild physical activities on their own (SPPB score >=6); 4. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals who are bedridden for a long time and have impaired limbs, or are in the stages of end-stage organ failure, terminal illness, or palliative care; 2. Have contraindications to exercise: myocardial infarction/stroke within the past 6 months, severe osteoporosis, or recent fracture history (within 3 months); 3. Cognitive impairment: MMSE score 1 month).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in relative skeletal muscle index (RSMI), grip strength (kg) and gait speed (m/s) before and after the intervention; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life;Intestinal Flora Composition;Hepatic and Renal Function, Blood Glucose;Adverse Events;Assessment of Physical Function;Metabolic and Nutritional Biomarkers;Nutritional Status; | — |
Countries
China
Contacts
Shanghai Putuo District People's Hospital