Osteoporotic low back pain
Conditions
Interventions
Trial Group:Ultrasound-guided paraspinal nerve injection (Triamcinolone acetonide injection 0.5mg + Lidocaine hydrochloride injection 2.5mg, 5ml per segment, up to 4 segments, once weekly for 2 sessio
Control Group:Intramuscular calcitonin injection (10 units per dose, once weekly for 3 months)
Sponsors
Affiliated Hospital of Jiangsu University
Eligibility
Sex/Gender
All
Age
45 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. The diagnostic criteria for primary OP comply with the diagnosis and treatment guidelines for primary OP formulated by the Chinese Medical Association; 2. Low back pain; 3. The course of disease is >=3 months; 4. Conservative treatments such as non-steroidal anti-inflammatory drugs and physical therapy cannot relieve pain; 5. Pain VAS score is >=4 points (i.e., 1-3 is mild, 4-6 is moderate, and 7-10 is severe); 6. Agree to this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with fresh spinal fractures and radiculopathy; 2. Concurrent with other spinal diseases (such as spinal stenosis, infection, tumor); 3. Having previously received other bone resorption inhibitors or bone formation promoters; 4. Severe impairment of important organ functions and abnormal coagulation function, puncture site infection; 5. Previous allergy to calcitonin drugs; 6. Fasting blood sugar > 10 mmol/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;Oswestry Disability Index;Lumbar forward flexion range of motion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver and kidney function;Calcium concentration;Adverse reactions;Withdrawal rate after half a year of treatment; | — |
Countries
China
Contacts
Public ContactLi Chunye
Affiliated Hospital of Jiangsu University
Outcome results
None listed